Virtual Presentations on HOS in mAb Design & Development
Fox® Hydroxyl Radical Protein Footprinting (HRPF) for mAb Drug Development
Fox® Hydroxyl Radical Protein Footprinting (HRPF) for mAb Aggregation
Fox® Protein Footprinting System Maps the Paratope and Epitope of TNFα Bound to Adalimumab
Educational Materials on Advanced Fox-Based HRPF
Structural Investigation of Therapeutic Antibodies Using Hydroxyl Radical Protein Footprinting Methods paper written by Dr. Corie Ralston of the Lawrence Berkeley National Laboratory and Prof. Joshua Sharp of The University of Mississippi and published in the journal Antibodies.
Interview with Dr. Joshua Sharp on Characterizing the HOS of mAbs
Hear about his recent article on the Structural Investigation of Therapeutic Antibodies Using Hydroxyl Radical Protein Footprinting Methods and how GenNext is engineering new technologies to answer difficult HOS questions.
Dr. Joshua Sharp from the University of Mississippi and GenNext Technologies
Dr. Sharp is a world-renowned expert with more than 25 peer-reviewed articles and numerous lectures on biopharmaceutical HRPF. Publishing the first benchtop methods for HRPF, Dr. Sharp’s innovations included the use of UV photolysis of hydrogen peroxide for hydroxyl radical generation. Along with his role as Chief Technology Officer for GenNext, Dr. Sharp is also an Associate Professor of Pharmacology and Research in the Research Institute of Pharmaceutical Sciences at the University of Mississippi. Professor Sharp serves on multiple national and international advisory and review panels as an expert on protein and carbohydrate biophysical and structural analysis by mass spectrometry.