Meet the GenNext Scientific Advisory Board

Meet Professor
David Tabb

Hear what Dr. Tabb from the Institut Pasteur has to say about key innovations in hardware and software that have transformed proteomics. And learn why revealing biological information with the right tools, removing roadblocks caused by black boxes, and continued bioinformatics education are important themes in his research. Then, he discusses why he joined the Scientific Advisory Board to help better understand the datasets produced by GenNext systems that probe protein structure.

Meet Professor
Lisa Jones

Professor Lisa Jones invented in-cell and in-vivo Fast Photo-Oxidation of Proteins (FPOP) to study cells and more complex model systems that could not be analyzed by Hydrogen Deuterium Exchange. Taking advantage of irreversible labeling, Lisa’s lab began to use FPOP to study disease pathogenesis in a new way. Most recently, her team is using FPOP to elucidate protein aggregation in different disease states.

Meet Professor
Michael Gross

Listen to Professor Michael Gross as he describes the invention of Fast Photo-Oxidation of Proteins (FPOP) for Hydroxyl Radical Protein Footprinting (HRPF). Professor Gross highlights how it is being applied in epitope mapping studies. He anticipates a great future for footprinting in antibody drug development for improved biotherapeutics.

Meet Dr. Mark Chance

Meet the world-famous father of HRPF, Dr. Mark Chance. In this interview, he describes being motivated to develop a new technique to see, with much greater resolution, proteins in motion. Living in the “magical middle ground” of moderate cost and higher resolution, Dr. Chance discusses his lab’s use HRPF technology to study neurological samples to detect the severity of a debilitating disease.

Meet Dr. Joshua Sharp

Watch as Genny™ the GenNext Fox interviews the internationally recognized expert in Hydroxyl Radical Protein Footprinting (HRPF)—Dr. Joshua Sharp. As the inventor of the first benchtop HRPF system and the pioneer of UV photolysis of hydrogen peroxide for hydroxyl radical generation, Josh has a lot of interesting things to say about the current success and future potential of protein footprinting.

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