Technologies for Higher Order Structural Analysis
Many structural biology researchers are looking for a way to make Higher Order Structural Analysis easier and more robust because they know how crucial a role it plays in biotherapuetic stability, safety, and biological function. Yet, traditional HOS approaches are known to be either complex, slow, dangerous, and expensive or unreliable, uninformative, and irreproducible. Choosing the best approach for your lab can be confusing with so many factors to consider.
Dr. Chea takes you through your options, explaining the pros and cons of each method. Then she will provide an overview of the Flash Oxidation (Fox™) Protein Footprinting System and how it is being applied in epitope mapping, mAb aggregation, and conformational analysis. By better understanding your options for higher order structure analysis, you can choose the method that empowers your lab to develop the safest and most effective biotherapeutics.
Presented by Emily Chea, PhD
Dr. Emily Chea received her PhD while studying with Professor Dr. Lisa Jones at the University of Maryland, Baltimore. Emily has made significant contributions to the development of HRPF, with particular emphasis on in-cell FPOP (IC-FPOP) for proteome-wide structural biology characterization of cellular drug–target interactions. Currently, Emily is a key member of the GenNext scientific team in her role as an Applied Research Scientist.