Introduction to Protein Footprinting

Presented by Professor Mark Chance of Case Western Reserve University and Professor Joshua Sharp of the University of Mississippi

This 60-minute webinar, hosted in association with Cambridge Healthtech Institute, provides an overarching review of and instruction in the theory behind protein footprinting techniques and applications. Receive instruction in the various benchtop covalent modification approaches as well as rapid labeling techniques such as X-ray synchrotron and Fast Photo-Oxidation of Protein (FPOP) hydroxyl radical protein foot-printing (HRPF). Examine the practical implications to applied research in biopharmaceutical research, protein interaction, biosimilar development, epitope mapping, paratope mapping, ligand-binding, drug-protein interaction, and conformational change analysis.

Prof. Sharp’s participation is supported in part by the National Institute of General Medical Sciences (R01GM127267).