Technologies for Higher Order Structural Analysis
ABSTRACT
Many structural biology researchers seek easier and more robust methods for Higher Order Structural (HOS) analysis, recognizing its critical role in biotherapeutic stability, safety, and function. Traditional HOS approaches can be complex, slow, dangerous, and costly, or unreliable and uninformative. With many factors to consider, choosing the best method for your lab can be challenging. Dr. Chea reviews various options, highlighting their pros and cons, and introduces the Flash Oxidation (Fox®) Protein Footprinting System. She explains its applications in epitope mapping, mAb aggregation, and conformational analysis, helping you select the best method for developing safe and effective biotherapeutics.
SPEAKER
Dr. Emily Chea received her PhD while studying with Professor Dr. Lisa Jones at the University of Maryland, Baltimore. Emily has made significant contributions to the development of HRPF, with particular emphasis on in-cell FPOP (IC-FPOP) for proteome-wide structural biology characterization of cellular drug–target interactions. Currently, Emily is a key member of the GenNext scientific team in her role as an Applied Research Scientist Manager.
