Introduction to Protein Footprinting

ABSTRACT

This 60-minute webinar, in collaboration with Cambridge Healthtech Institute, offers a comprehensive review and instruction in protein footprinting techniques and applications. Learn about various benchtop covalent modification methods and rapid labeling techniques like X-ray synchrotron and Fast Photo-Oxidation of Protein (FPOP) hydroxyl radical protein footprinting (HRPF). Explore their practical implications for biopharmaceutical research, protein interactions, biosimilar development, epitope and paratope mapping, ligand-binding, and conformational change analysis.

SPEAKERS

Professor Chance is an internationally recognized expert in proteomics and structural biology who has built multiple science and training programs over a 30-year career in academia. He has published over 300 papers with over 15,000 citations. He is currently Vice Dean for Research and holds the titles of Distinguished University Professor, the Charles W. and Iona A. Mathias Professor of Cancer Research, as well as Professor appointments in the Departments of Nutrition, Genetics & Genome Sciences, and General Medical Sciences at the School of Medicine of Case Western Reserve University (CWRU). He is the founding director (since 2005) of the Center for Proteomics and Bioinformatics and founding director of the Center for Synchrotron Biosciences (since 1994). Prior to his appointment at CWRU, Dr. Chance was professor of Physiology and Biophysics at Albert Einstein College of Medicine.

Dr. Joshua Sharp is an internationally recognized expert in HRPF, pioneering novel MS-based technology to study HOS focusing on the structure-function relationships of proteins and carbohydrates. With more than 21 peer-reviewed articles, Dr. Sharp has also presented numerous invited lectures around the world. Along with acting as the Chief Technology Officer of GenNext, Dr. Sharp is also Associate Professor of Pharmacology, Associate Professor of Chemistry and Biochemistry, and Director of the Glycoscience Center of Research Excellence at the University of Mississippi.

REGISTRATION FORM

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